ataxia telangiectasia mutated造句

例句与造句

1. The gene is called ATM ( for ataxia telangiectasia mutated ).
2. For instance two dominant-negative germ line mutations were identified in the Ataxia telangiectasia mutated ( ATM ) gene which increases susceptibility to breast cancer.
3. In the presence of ionizing radiation ( IR ), the Smc1 subunit of cohesin is phosphorylated by the ataxia telangiectasia mutated ( ATM ) kinase.
4. Ataxia telangiectasia mutated ( ATM ) is a kinase that ( similar to mTOR ) can phosphorylate KAP1 resulting in the switch from viral latency to the lytic cycle.
5. The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 ( breast cancer 1 ) protein and the ATM ( ataxia telangiectasia mutated ) protein.
6. It's difficult to find ataxia telangiectasia mutated in a sentence. 用ataxia telangiectasia mutated造句挺难的
7. The cancers associated with the gene, called the ATM ( for ataxia telangiectasia mutated ), include those of the breast, lung, stomach, skin and pancreas.
8. Ataxia telangiectasia results from defects in the ataxia telangiectasia mutated gene, which can cause abnormal cell death in various places of the body, including brain areas related to coordinated movement of the eyes.
9. The rapid response involves phosphorylation events that initiate with either kinase ATM ( Ataxia telangiectasia mutated ) or ATR ( Ataxia Telangiectasia and Rad3 related ), which act as sensors, depending on the type of damage.
10. Central to all DNA damage induced checkpoints responses is a pair of large protein kinases belonging to the first group of PI3K-like protein kinases-the ATM ( Ataxia telangiectasia mutated ) and ATR ( Ataxia-and Rad-related ) kinases, whose sequence and functions have been well conserved in evolution.
11. At a DSB, MRE11-RAD50-NBS1 ( MRN ) protein complex recruits ataxia telangiectasia mutated ( ATM ) kinase which phosphorylates Serine 129 of Histone 2A . MDC1, mediator of DNA damage checkpoint 1, binds to the phosphopeptide, and phosphorylation of H2AX may spread by a positive feedback loop of MRN-ATM recruitment and phosphorylation.
12. The TERF1 encoded protein has been shown to have interactions with the following; SALL1 ( Sal-like1-Drosophila, a protein . ), ATM ( Ataxia telangiectasia mutated, a protein kinase ), PINX1 ( TERF1-interacting telomerase inhibitor 1 ), TINF2 ( TERF1-interacting telomerase nuclear factor ), TNKS2 ( Tankyrase, an enzyme ) and NME1 ( nucleoside diphosphate kinase ) . In conclusion, as mentioned above, the telomeric repeat-binding factor 1 protein has most of its functions related to the binding of components and regulation of processes.